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Organic 5-HTP (56-69-9) 98% Powder

Griffonia simplicifolia is a legume and belongs to the Fabaceae family. Griffonia simplicifolia is commonly known as Atooto, Kanya, Kajya, gbogbotri, kwakuo-aboto. West Africa is the native place of this shrub. Griffonia simplicifolia seeds are a well-recognized abundant natural source of 5-hydroxytryptophan (5-HTP). The 5-HTP is generally used as an alternative treatment for a serotonin imbalance.
What is 5-HTP?
5-HT is also known as 5-hydroxytryptamine, a direct precursor and enhancer of the activity of the brain hormone serotonin. Griffonia simplicifolia contains an abundant amount of 5-HTP. 5-HTP is converted to 5-HT after entering the central nervous system because of tryptophan decarboxylase enzymatic activity. It has been found that 5-HTP stimulates 5-HT receptors in the brain only after conversion to 5-HT. 5-HTP, alternatively known as 5htp, 5 htp, 5-Hydroxytryptophan, Griffonia Seed Extract, Griffonia simplicifolia, Griffonia simplicifolia Extract, Griffonia Extract, Griffonia simplicifolia seed Extract, L-5-Hydroxytryptophan, L-5 Hydroxy Tryptophan, etc.
The CAS number of 5-HTP is 56-69-9. The molecular formula is C11H12N2O3. The solubility of 5-HTP differs depending on the solvent. The solubility of 5-HTP is 2.5 g/100 mL in 50% boiling alcohol and 5.5 g/100 mL in water at 100 °C. The molecular weight of 5-HTP is 220.22. 5-HTP extracted from Griffonia simplicifolia seeds is a light gray-white fine powder with slight air and salty taste.
Constituents of Griffonia Simplicifolia seed Extract
The primary constituent of Griffonia Simplicifolia seed extract is 5-HTP. Other significant constituents of Griffonia Simplicifolia seed extract are the β-carboline alkaloid derivative griffonine and other alkaloids. 1,1′-ethylidenebis(l-tryptophan), 3-(phenylamino)alanine, and some more nitrogen-containing compounds are also present in Griffonia Simplicifolia seed extract. Griffonia Simplicifolia seed extract also contains unsaturated fatty acids.
5-HTP forms and specifications
Different variety of 5-HTP is extracted from Griffonia Simplicifolia seed extract. Some of the significant 5-HTP forms and specifications are 99% High Purity 5-HTP powder, Purified 98%+ Griffonia Seed Extract, and 95% 5-HTP granules. Apart from these, custom standardized 5-HTP powder extract with 10-99% purities.
5-HTP vs l-theanine
The 5-HTP is an amino acid that the body produces naturally in form of the essential amino acid tryptophan. 5-HTP is used in the body for serotonin production. 5-HTP is required in case of insufficient serotonin levels that lead to depression, anxiety disorder, sleep disturbance, and weight gain. Some plant sources like Griffonia Simplicifolia seed extract are abundant sources of natural 5-HTP.
L-theanine is an amino acid that is extracted from tea (both green and black) and mushrooms. Some dietary manufacturing companies manufacture L-theanine-containing pills or tablets. The primary use of L-theanine is to get a relaxing effect. However, it is useful for anxiety and stress relief. L-theanine may improve focus attention, and immune system functioning. L-theanine also acts as an adjuvant therapy along with certain chemotherapy drugs for amplifying the anti-tumor effects. It also suggested controlling blood pressure during stressful situations.
The mechanism of 5-HTP and L-theanine differs. L-theanine primarily increases alpha-wave activity. But it also acts as a neurotransmitter serotonin and GABA activity stimulator. The 5-HTP is a precursor to serotonin and melatonin that increases REM sleep.
Both 5-HTP and L-theanine are used for sleep and relaxation support. However, a dose of 5-HTP is lesser compared to L-theanine. The dose of 5-HTP is 2 mg/kg per day at bedtime for children and 50 to 300 mg dose per day at bedtime for adults. The L-theanine dose may rise to 400 mg daily for both adults and children. However, the dose may be given in divided dosages.
5-HTP and St. John’s Wort
5-HTP is an anti-depressant and effective treatment option for patients who have resistance to conventional therapy. 5-HTP supplementation helps to improve mental well-being and relaxation. St John’s Wort is a phytochemical extracted from Hypericum perforatum, a star-shaped yellow flower. St John’s Wort is also popular for depression management. However the efficacy of St John’s Wort as an anti-depressant is debatable as placebo-controlled research study findings reported no improvement for depression treatment. The primary difference between 5-HTP and St John’s Wort is that 5-HTP activates serotonin production in the body while St John’s Wort prevents serotonin- re-absorption. Research study findings reported that 5-HTP has high levels of efficacy with mild to moderate side effects risk. The efficacy of St John’s Wort is debatable.
Where to buy bulk 5-HTP powder
Luck Herb is a well-established Chinese natural ingredient manufacturer and supplier. The quality of the products available in Luke Herb is genuine. The quality control department of Luke Herb has its quality control department to thoroughly checks every step from the raw material collection to the packing of the finished product. Luck Herb is a single stop of commonly used natural ingredients like Griffonia simplicifolia seed Powder extract containing 5-HTP. The call to action for authentic buyers is simple. Just contact Luck Herb, and send a quotation request to get technical documents.

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